Dolutegravir+emtricitabine+tenofovir Alafenamide
About Dolutegravir+emtricitabine+tenofovir Alafenamide
Dolutegravir+emtricitabine+tenofovir Alafenamide is used for the treatment of HIV-1 infection (human immunodeficiency virus type 1) in adults and children above 12 years weighing at least 40 kg.
Dolutegravir+emtricitabine+tenofovir Alafenamide contains Dolutegravir, Emtricitabine, and Tenofovir alafenamide. These medicines work together to block the activity of HIV integrase and reverse transcriptase enzymes that the virus needs to multiply, thereby reducing the amount of virus in the body and helping to treat HIV infection.
Take Dolutegravir+emtricitabine+tenofovir Alafenamide exactly as prescribed by your doctor. Swallow it whole with a glass of water, and do not crush or chew it. In some cases, Dolutegravir+emtricitabine+tenofovir Alafenamide may cause common side effects such as trouble sleeping, headache, nausea, and tiredness. Please talk to your doctor if these side effects persist or worsen.
Consult your doctor before taking Dolutegravir+emtricitabine+tenofovir Alafenamide if you are pregnant or planning to get pregnant. Avoid breastfeeding while taking Dolutegravir+emtricitabine+tenofovir Alafenamide. Dolutegravir+emtricitabine+tenofovir Alafenamide does not reduce the risk of getting HIV-1 infection through sexual contact; therefore, it is important to practise safe sex to avoid transmitting HIV to your partner.
Uses of Dolutegravir+emtricitabine+tenofovir Alafenamide
Medicinal Benefits
- Dolutegravir+emtricitabine+tenofovir Alafenamide is an antiretroviral medication that is highly effective in treating HIV-1 infection.
- It keeps HIV infection under control by quickly reducing the amount of virus in the body.
- It helps recover and maintain immune system health by effectively suppressing HIV replication.
- It lowers the risk of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related complications.
Directions for Use
- Dolutegravir+emtricitabine+tenofovir Alafenamide can be taken with or without food, or as advised by a doctor.
- Generally, Dolutegravir+emtricitabine+tenofovir Alafenamide is taken once daily, or as prescribed by your doctor.
- Swallow Dolutegravir+emtricitabine+tenofovir Alafenamide as a whole with a glass of water.
- Do not crush, chew, or break it.
Storage
Side Effects of Dolutegravir+emtricitabine+tenofovir Alafenamide
- Headache
- Tiredness
- Trouble sleeping
- Nausea
Drug Warnings
- Inform your doctor if you are allergic to any of the ingredients of Dolutegravir+emtricitabine+tenofovir Alafenamide.
- Consult your doctor before taking Dolutegravir+emtricitabine+tenofovir Alafenamide if you are pregnant or planning to get pregnant.
- Avoid breastfeeding while undergoing treatment with Dolutegravir+emtricitabine+tenofovir Alafenamide.
- Practise safe sex to avoid transmitting HIV to your partner.
- Inform your doctor if you have hepatitis infection, diabetes, hypertension, or any liver/heart/kidney problems.
- Keep your doctor informed about any other medications you are taking to rule out any side effects or interactions.
Drug Interactions
Drug-Drug Interactions: Dolutegravir+emtricitabine+tenofovir Alafenamide may interact with certain medicines, potentially increasing side effects or altering their effectiveness. Inform your doctor if you are taking any of the following:
- Drugs used for heart rhythm disorders (Dofetilide)
• Potential effect: May reduce the effectiveness of Dolutegravir+emtricitabine+tenofovir Alafenamide and increase the risk of an irregular heart rhythm. - Anti-HIV drugs (Lamivudine, Efavirenz)
• Potential effect: May reduce the blood levels and effectiveness of these medications. - Anticancer drugs (Streptozocin)
• Potential effect: May increase the risk of kidney problems. - Minerals and electrolytes (Calcium citrate, Magnesium chloride)
• Potential effect: May reduce the effectiveness of Dolutegravir+emtricitabine+tenofovir Alafenamide. - Antacids (Aluminium hydroxide)
• Potential effect: May reduce the effectiveness of Dolutegravir+emtricitabine+tenofovir Alafenamide. - Antiretrovirals (Didanosine)
• Potential effect: May increase the blood levels and risk of Didanosine side effects. - Medicine used to prevent seizures (Fosphenytoin)
• Potential effect: May reduce the effectiveness of Dolutegravir+emtricitabine+tenofovir Alafenamide.
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Dolutegravir+emtricitabine+tenofovir Alafenamide should be used with caution or avoided in people with:
- A known hypersensitivity disorder (allergic reaction)
- Diabetes (high blood sugar)
- Hypertension (high blood pressure)
- Hepatitis (liver inflammation)
- Any liver, kidney, or heart disease
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeIt is not recommended to consume alcohol with Dolutegravir+emtricitabine+tenofovir Alafenamide. Please consult your doctor if you have any concerns.
Pregnancy
cautionPlease consult your doctor if you are pregnant. Your doctor will prescribe if the benefits are found to outweigh the risks.
Breast Feeding
unsafeAvoid breastfeeding while on treatment with Dolutegravir+emtricitabine+tenofovir Alafenamide.
Driving
cautionDolutegravir+emtricitabine+tenofovir Alafenamide may cause dizziness and tiredness. Do not drive if you experience any side effects after using Dolutegravir+emtricitabine+tenofovir Alafenamide.
Liver
cautionExercise caution before using Dolutegravir+emtricitabine+tenofovir Alafenamide in case of established liver disease. Please consult your doctor to address any concerns.
Kidney
cautionExercise caution before using Dolutegravir+emtricitabine+tenofovir Alafenamide in case of established kidney disease. Please consult your doctor to address any concerns.
Children
unsafeDolutegravir+emtricitabine+tenofovir Alafenamide is not recommended for use in children under 12 years of age. Please consult your doctor in case of any concerns.
Habit Forming
Diet & Lifestyle Advise
Dietary choices:
- Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to support overall health.
Physical activity:
- Take a stroll in the garden or spend 30 minutes of your time doing some light physical activity daily, but avoid over-exertion if you feel too tired.
- Practice meditation and yoga to help maintain a healthy mind and body.
Preventive measures:
- Practise safe sex to prevent transmitting HIV to your partner.
- Use a condom during intercourse whenever possible.
- Educate yourself and your partner about pre- and post-exposure prophylaxis and ART (anti-retroviral therapy).
Oral hygiene:
- Take good care of your oral hygiene, as HIV often causes oral sores.
- Brush, floss, and scrape your tongue well and keep your mouth clean.
- See a dentist routinely to maintain oral health.
Patients Concern
Disease/Condition Glossary
HIV infection: HIV (human immunodeficiency virus) is a virus that weakens the immune system by destroying white blood cells, making the body more vulnerable to other infections and illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, tiredness, and muscle aches. HIV is a lifelong condition with no definite cure, but it can be managed with antiretroviral drugs.
FAQs
Dolutegravir+emtricitabine+tenofovir Alafenamide is used for the treatment of HIV-1 infection (human immunodeficiency virus type 1) in adults and children above 12 years weighing at least 40 kg.
Dolutegravir+emtricitabine+tenofovir Alafenamide contains Dolutegravir, Emtricitabine, and Tenofovir alafenamide. These medicines work together to block the activity of HIV integrase and reverse transcriptase enzymes that the virus needs to multiply, thereby reducing the amount of virus in the body and helping to treat HIV infection.
It is not known if Dolutegravir+emtricitabine+tenofovir Alafenamide is safe for patients who have HIV-1 and hepatitis-B infections. Please consult your doctor for any concerns.
Do not stop taking Dolutegravir+emtricitabine+tenofovir Alafenamide without consulting your doctor, as it may reduce the effectiveness of anti-HIV therapy. Continue taking Dolutegravir+emtricitabine+tenofovir Alafenamide for as long as your doctor has prescribed it to you to treat your condition effectively. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Dolutegravir+emtricitabine+tenofovir Alafenamide.
Dolutegravir+emtricitabine+tenofovir Alafenamide might cause lactic acidosis (excess of lactic acid in the blood). Consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, or deep, rapid breathing.
Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
Avoid nursing while receiving Dolutegravir+emtricitabine+tenofovir Alafenamide therapy. Avoid alcohol consumption. It is critical to engage in safe sex to avoid transferring HIV to your partner.
Before taking the Dolutegravir+emtricitabine+tenofovir Alafenamide, let your doctor know about all your medical conditions, sensitivities, and all the medications you are using. And inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Yes, Dolutegravir+emtricitabine+tenofovir Alafenamide is an anti-retroviral drug used in the treatment of HIV-1 infection.
Your doctor will determine the duration of Dolutegravir+emtricitabine+tenofovir Alafenamide based on your medical condition and response to treatment.
The recommended dosage of Dolutegravir+emtricitabine+tenofovir Alafenamide is one tablet taken orally once daily. However, dosage may vary depending on various factors, including medical condition and treatment response.
Dolutegravir, Emtricitabine and Tenofovir Alafenamide are the key active ingredients present in Dolutegravir+emtricitabine+tenofovir Alafenamide.
Dolutegravir+emtricitabine+tenofovir Alafenamide is not recommended for use in children under 12 years of age. Please consult your doctor in case of any concerns.
Taking more than the recommended dosage does not provide additional pain relief and can increase the risk of adverse effects.
Avoid consuming alcohol along with Dolutegravir+emtricitabine+tenofovir Alafenamide as it could lead to adverse effects.
